J&J Medical Connect
INVEGA SUSTENNA®

(paliperidone palmitate)

This information is intended for US healthcare professionals to access current scientific information about J&J Innovative Medicine products. It is prepared by Medical Information and is not intended for promotional purposes, nor to provide medical advice.

INVEGA SUSTENNA - Administration - Injection instructions

Last updated: 05/09/2025

Specific response

INVEGA SUSTENNA is injected slowly, deep into the muscle1

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  • Attach the needle to the syringe using a gentle twisting motion.
  • Always check for damage or leaks prior to administration.
  • Alternate future injections between the 2 gluteal or deltoid muscles.

References

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1. INVEGA SUSTENNA [(paliperidone palmitate) Extended-Release Injectable Suspension] [Prescribing Information]. Titusville, NJ: Janssen Pharmaceuticals, Inc; https://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/INVEGA+SUSTENNA-pi.pdf.

2.Yin J, Collier AC, Barr AM, et al. Paliperidone palmitate long-acting injectable given intramuscularly in the deltoid versus the gluteal muscle: are they therapeutically equivalent. J Clin Psychopharmacol. 2015;35(4):447-449.