(paliperidone palmitate)
This information is intended for US healthcare professionals to access current scientific information about J&J Innovative Medicine products. It is prepared by Medical Information and is not intended for promotional purposes, nor to provide medical advice.
INVEGA SUSTENNA® (paliperidone palmitate)
Medical Information
INVEGA SUSTENNA - Specific populations - Concomitant use with CYP3A4/P-glycoprotein inducers
Last updated: 05/09/2025
Specific response
Avoid using a strong inducer of CYP3A4 and/or P-gp (e.g., carbamazepine, rifampin, St John’s Wort) during a dosing interval for INVEGA SUSTENNA. If administering a strong inducer is necessary, consider managing the patient using paliperidone ER tablets.1
CYP, cytochrome P450; ER, extended release; P-gp, P-glycoprotein.
Reference
Show Hide
1.INVEGA SUSTENNA [(paliperidone palmitate) Extended-Release Injectable Suspension] [Prescribing Information]. Titusville, NJ: Janssen Pharmaceuticals, Inc; https://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/INVEGA+SUSTENNA-pi.pdf.
