J&J Medical Connect
INVEGA SUSTENNA®

(paliperidone palmitate)

This information is intended for US healthcare professionals to access current scientific information about J&J Innovative Medicine products. It is prepared by Medical Information and is not intended for promotional purposes, nor to provide medical advice.

INVEGA SUSTENNA® (paliperidone palmitate)

Medical Information

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INVEGA SUSTENNA - Administration - General administration instructions

Last updated: 05/09/2025

Specific response

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Administered ONLY by a health care professional1

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Each INVEGA SUSTENNA extended-release injectable suspension is intended for IM use only1

  • DO NOT administer via any other route

  • Avoid inadvertent injection into a blood vessel

  • Administer dose in a single injection; DO NOT administer in divided injections

  • Inject slowly, deep into the muscle

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ONLY use needles provided in the INVEGA SUSTENNA kit.1

  • DO NOT substitute these needles with commercially available safety needles as they may have a different dead space volume that may result in the administration of a lower or higher INVEGA SUSTENNA dose.2

HCP, health care provider; IM, intramuscular.

References

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1. INVEGA SUSTENNA [(paliperidone palmitate) Extended-Release Injectable Suspension] [Prescribing Information]. Titusville, NJ: Janssen Pharmaceuticals, Inc; https://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/INVEGA+SUSTENNA-pi.pdf.

2. Data on File. Janssen Research & Development. 2014.