This information is intended for US healthcare professionals to access current scientific information about J&J Innovative Medicine products. It is prepared by Medical Information and is not intended for promotional purposes, nor to provide medical advice.

TREMFYA® Prefilled Pen 100 mg/mL – Preparation

Change dosage

Last updated: 08/10/2026

You will need:

One 100 mg Prefilled Pen

Not provided in the carton:

Alcohol swabs

Adhesive bandages

Cotton balls or gauze pads

Sharps container

STEP 1: Get ready

Allow TREMFYA PEN to come to room temperature and inspect the carton.

Remove the carton from the refrigerator and let the carton sit on a flat surface at room temperature for approximately 30 minutes before use.

Do not warm the TREMFYA PEN any other way.

Check to see that you have the correct medicine and dose.

Check the expiration (EXP) date.

Do not use TREMFYA PEN if the expiration date has passed or if the seal on the carton is broken.

Contact your healthcare provider or pharmacist for a new TREMFYA PEN.

STEP 2: Inspect TREMFYA PEN

Take your TREMFYA PEN out of the carton and check the liquid in the viewing window.

It should be clear and colorless to slightly yellow and may contain tiny white or clear particles. You may also see air bubbles. This is normal.

Do not inject if the liquid:

  • is cloudy
  • is discolored
  • has large particles

Contact your healthcare provider or pharmacist for a new TREMFYA PEN.

STEP 3: Choose injection site

Select from the following areas for injection:

  • Front of thighs
  • Lower stomach area (lower abdomen), except for a 2-inch area right around your navel (belly button)
  • Back of upper arms (only for adults and only if someone else is giving you the injection). This injection site is not for use in children

Do not inject into skin that is tender, bruised, red, scaly, thick, or hard.

Avoid areas with scars or stretch marks.

STEP 4: Wash hands and clean injection site

Wash your hands well with soap and warm water.

Wipe your chosen injection site with an alcohol swab and allow it to dry.

Do not touch, fan, or blow on the injection site after you have cleaned it.

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