This information is intended for US healthcare professionals to access current scientific information about J&J Innovative Medicine products. It is prepared by Medical Information and is not intended for promotional purposes, nor to provide medical advice.

TREMFYA® Prefilled Pen 100 mg/mL – Injection

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Last updated: 08/10/2026

STEP 1: Remove the cap when you are ready to inject

Do not touch the teal needle guard. This may start the injection, and you will not receive the dose.

Pull the cap straight off. It is normal to see a few drops of liquid.

Inject TREMFYA PEN within 5 minutes of removing the cap.

Do not put the cap back on as this may damage the needle.

Do not use your TREMFYA PEN if it is dropped after removing the cap.

Contact your healthcare provider or pharmacist for a new TREMFYA PEN.

STEP 2: Position TREMFYA PEN straight onto the injection site, then push and hold

Do not lift your TREMFYA PEN during injection. If you do, the teal needle guard will lock and the full dose will not be delivered.

Position your TREMFYA PEN straight onto the injection site, with the teal needle guard against the skin and the viewing window facing you.

Press down on TREMFYA PEN and keep holding it down against the skin.

You will hear the first click.

STEP 3: Keep holding your TREMFYA PEN firmly against the skin for about 10 seconds to hear a second click

STEP 4: Confirm injection is complete

Keep holding firmly against the skin and confirm your injection is complete.

Your injection is complete when the plunger rod stops moving and fills the viewing window.

STEP 5: Lift straight up

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