What is the Recommended Dosing for UPTRAVI Tablets for Pulmonary Arterial Hypertension?

important information about uptravi

• Before you take UPTRAVI, tell your healthcare provider if you have narrowing of the pulmonary veins, a condition called pulmonary veno-occlusive disease.¹

summary

Here is a passage from the UPTRAVI PRESCRIBING INFORMATION and PATIENT INFORMATION which may be helpful to address your question:

What is the recommended dosing for UPTRAVI tablets for pulmonary arterial hypertension?

• The recommended starting dosage of UPTRAVI tablets for adult patients is 200 micrograms (mcg).¹
  • UPTRAVI is usually taken 2 times each day.
• The recommended starting dose of UPTRAVI for pediatric patients 2 years and older is determined based on the patient’s body weight.¹
  • UPTRAVI is usually taken 2 times each day.
• Your healthcare provider will slowly increase your or your child’s dose to find the dose of UPTRAVI that is right.¹ 
  • If you or your child have side effects, your healthcare provider may tell you to change the dose of UPTRAVI.
• UPTRAVI can be taken with or without food.¹
  • Taking UPTRAVI with food may help you or your child tolerate UPTRAVI better.
• Swallow UPTRAVI tablets whole.¹
  • Do not split or crush UPTRAVI tablets.
• If you or your child cannot swallow the tablets¹:
  • Dissolve (disperse) the 100 mcg or 150 mcg tablet(s) in apple or orange juice. Do not disperse the tablet(s) in water or milk.
    • Place the required number of tablet(s) for the prescribed dose in a cup. Do not crush or split the tablet(s).
    • Add 1 or 2 teaspoons of apple or orange juice to the prescribed number of tablets.
    • Wait for 5 minutes, then stir the juice and the tablet(s) until the tablets are dispersed.
    • Take or give the mixture right away.
  • UPTRAVI tablets can also be given with soft foods as follows:
    • Cover the prescribed number of 100 mcg or 150 mcg tablets with a small amount of soft food, such as yogurt, applesauce or mashed bananas.
    • Take or give the mixture right away. Make sure no remaining medicine is left in the container by adding more soft food and take or give the mixture right away.

Do not store UPTRAVI tablets that are already mixed with juice or soft food for later use.¹

• If you or your child miss a dose of UPTRAVI, take it as soon as you remember. If the next scheduled dose is due within 6 hours, skip the missed dose. Take the next dose at the regular time.¹
• If you or your child miss 3 or more days of UPTRAVI, call your healthcare provider to see if the dose needs to be changed.¹
• If you or your child take too much UPTRAVI, call your healthcare provider or go to the nearest hospital emergency room right away.¹

additional information

This information is provided ONLY in response to your request and is not intended as medical advice, to promote the use of our product, or suggest using it in any manner other than as described in the PRESCRIBING INFORMATION. All decisions regarding your medical treatment should be made with your healthcare professional(s). Please contact your healthcare professional(s) to discuss the information in this response.

Please refer to the attached full PRESCRIBING INFORMATION and the PATIENT INFORMATION for UPTRAVI.¹