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UPTRAVI® (selexipag)
Patient Medical Information

What are the Possible Side Effects of UPTRAVI?

Last Updated: 06/03/2026

IMPORTANT INFORMATION ABOUT UPTRAVI

  • Before you take UPTRAVI, tell your healthcare provider if you have narrowing of the pulmonary veins, a condition called pulmonary veno-occlusive disease.1

summary

Here is a passage from the UPTRAVI PATIENT INFORMATION which may be helpful to address your question:

What are the possible side effects of UPTRAVI?

  • The most common side effects of UPTRAVI in adults and children include1:
    • headache
    • jaw pain
    • muscle pain
    • pain in arms or legs
    • diarrhea
    • nausea
    • vomiting
    • flushing
  • Additional common side effects of UPTRAVI in adults include1:
    • pain in joints
    • low red blood cell count
    • redness, pain, or swelling at the injection site
    • rash
    • decreased appetite
  • Additional common side effect in children includes stomach (abdominal) pain.1
  • These are not all of the possible side effects of UPTRAVI.1
    • Call your doctor for medical advice about side effects. You may report side effects to the Food and Drug Administration (FDA) at 1-800-FDA-1088.

additional information

This information is provided ONLY in response to your request and is not intended as medical advice, to promote the use of our product, or suggest using it in any manner other than as described in the PRESCRIBING INFORMATION. All decisions regarding your medical treatment should be made with your healthcare professional(s). Please contact your healthcare professional(s) to discuss the information in this response.

Please refer to the attached full PRESCRIBING INFORMATION and the PATIENT INFORMATION for UPTRAVI.1

 

References

1 UPTRAVI (selexipag) [Prescribing Information]. Titusville, NJ: Actelion Pharmaceuticals US, Inc, a Janssen Pharmaceutical Company: Actelion Pharmaceuticals US, Inc; https://www.jnjlabels.com/package-insert/product-monograph/prescribing-information/UPTRAVI-pi.pdf
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