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ICOTYDE™ (icotrokinra)

Patient Medical Information

What are the Possible Side Effects of ICOTYDE?

Last Updated: 03/18/2026

summary

Here is a passage from the ICOTYDE MEDICATION GUIDE which may be helpful to address your question:

What is the most important information I should know about ICOTYDE?

  • Infections. Medicines that interact with the immune system, such as ICOTYDE, may lower your ability to fight infections and may increase your risk of infections. Your healthcare provider may check you for infections and tuberculosis (TB) before starting treatment and may treat you for TB before you begin treatment with ICOTYDE if you have a history or TB or have active TB. Your healthcare provider should watch you closely for signs and symptoms of TB during and after treatment with ICOTYDE. Tell your healthcare provider right away if you have any infection or have symptoms of an infection, including1:
    • fever, sweat, or chills
    • cough
    • shortness of breath
    • blood in your mucus (phlegm)
    • muscle aches
    • warm, red, or painful skin or sores on your body different from your psoriasis
    • weight loss
    • diarrhea or stomach pain
    • burning when you urinate or urinating more often than normal

The most common side effects of ICOTYDE include: 

  • headache1 
  • nausea1 
  • cough1 
  • fungal infection1 
  • tiredness1 

These are not all the possible side effects of ICOTYDE.1 

Call your doctor for medical advice about side effects. You may report side effects to Food and Drug Administration (FDA) at 1800FDA1088.1 

ADDITIONAL INFORMATION

This information is provided ONLY in response to your request and is not intended as medical advice, to promote the use of our product, or suggest using it in any manner other than as described in the PRESCRIBING INFORMATION. All decisions regarding your medical treatment should be made with your healthcare professional(s). Please contact your healthcare professional(s) to discuss the information in this response.

Please refer to the attached full PRESCRIBING INFORMATION and the MEDICATION GUIDE for ICOTYDE.1 

 

References

1 ICOTYDE (icotrokinra) [Prescribing Information]. Horsham, PA: Janssen Biotech, Inc.; https://www.jnjlabels.com/package-insert/product-monograph/prescribing-information/ICOTYDE-pi.pdf
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