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Immunology

Congress Materials – United European Gastroenterology Week (UEGW 2026)

 

2026 United European Gastroenterology Week | Oct 17-20 | Barcelona, Spain

This section includes selected Johnson & Johnson Innovative Medicine abstracts, posters, or oral presentations, which have been accepted for congress presentations in the last 2 years or less (as determined by any congress restrictions on length of time materials can be posted). Information about pipeline products or investigational uses of products does not imply FDA approval for these products or uses, nor does it establish the safety or efficacy of these products or uses. Johnson & Johnson does not recommend or suggest use of its medicines in a manner inconsistent with FDA-approved labeling. The content contained in this section is subject to congress copyright permissions.

ARGES-UC V2.0: Artificial Intelligence-Derived Endoscopic Severity Scoring and Disease Characterization in Ulcerative Colitis

Krishna Chaitanya, Natalia Alves, Pooya Mobadersany, Chaitanya Parmar, Louis Ghanem, Camilla Richmond, Els Van Limbergen, Paul J. Ufberg, Richard Strauss, Sheri Volger, Yuliya Halchenko, Nicholas Skomrock, Tommaso Mansi, Gabriela Cula, Kristopher Standish, Pablo F. Damasceno


This document will be available on Oct 20th 2026

Assessment of Inflammatory Bowel Disease-Specific Quality of Life (IMPACT-III) Symptoms After Treatment With Ustekinumab in Pediatric Ulcerative Colitis

Els Van Limbergen, Anne M. Griffiths, Sheri Volger, Lilianne Kim, Gary Mao, Richard Strauss, Paul J. Ufberg, Robert Fieo


This document will be available on Oct 17th 2026

Association of Endoscopic Healing With Clinical Outcomes in Inflammatory Bowel Disease: A Retrospective Study

Elise Wu, Dominik Naessens, Jackie Kwong, Karthik Murugadoss, Sunil Kumar Ravi, Devrata Puri


This document will be available on Oct 17th 2026

Changes in Intestinal Stenosis Among Patients With Moderately to Severely Active Crohn’s Disease Treated With Guselkumab: Results From the Phase 3 GALAXI and GRAVITI Studies

Walter Reinisch, Anita Afzali, Hamid Bassiri, Rian Van Rampelbergh, Wilbert van Duijnhoven, Shashi Adsul, Dylan J. Richards, Nat A. Terry, David T. Rubin, on behalf of the GALAXI and GRAVITI Investigators


This document will be available on Oct 18th 2026

Computer-Vision Assessment of Endoscopic Disease Severity in Subjects With and Without Prior Exposure to Advanced Therapies Across Adult and Pediatric Ulcerative Colitis Clinical Trials

Natalia Alves, Krishna Chaitanya, Pooya Mobadersany, Chaitanya Parmar, Louis Ghanem, Camilla Richmond, Els Van Limbergen, Paul J. Ufberg, Richard Strauss, Sheri Volger, Nicholas Skomrock, Gabriela Cula, Kristopher Standish, Pablo F. Damasceno


This document will be available on Oct 17th 2026

Deep Remission in Guselkumab-Treated Participants With Moderately to Severely Active Crohn’s Disease Through 3 Years: Results From the GALAXI 2 & 3 Studies

David T. Rubin, Anita Afzali, Christopher Busse, Rian Van Rampelbergh, Wilbert van Duijnhoven, Marla Dubinsky, Geert R. D’Haens


This document will be available on Oct 19th 2026

Early Improvement of Inflammatory Biomarkers Predicts 1-Year Outcomes in Adults With Crohn’s Disease Treated With Guselkumab: Pooled GALAXI 2 & GALAXI 3, Phase 3 Trials Analysis

Marc Ferrante, Alessandro Armuzzi, Raja Atreya, Tim Raine, Rian Van Rampelbergh, Jacqueline van Denderen, Maciej Nazar, Victoria McCaffrey, Mathurin Fumery


This document will be available on Oct 18th 2026

Early Symptomatic Response to Guselkumab in Inflammatory Bowel Disease: First Real-World Data From the German GORGEOUS Study

Stefan Schubert, Robert Ehehalt, Wilfried Landry, Christoph Jochum, Elisabeth Schnoy, Fabian Kreimendahl, Terry-Lisa Ly, Eva Hundt, Kathleen Vogel, Lukas Scharfenberger


This document will be available on Oct 17th 2026

Efficacy and Safety of Guselkumab in Perianal Fistulizing Crohn’s Disease: Week 48 Results from the Phase 3, Randomized, Double-Blind, Placebo-Controlled FUZION Trial

Ailsa Hart, Axel Dignass, Vipul Jairath, Tadakazu Hisamatsu, Bruce E. Sands, Antonino Spinelli, Susan J. Connor, André D’Hoore, Walter Reinisch, Silvio Danese, David A. Schwartz, Julian Panés, Bram Verstockt, Anton Stift, Maciej Nazar, Jacqueline van Denderen, Takehiko Sakamoto, Koji Masuda, Stephen Xu, Ivana Bravatà, Geert D’Haens, Laurent Peyrin-Biroulet, on behalf of the FUZION Study Group


This document will be available on Oct 19th 2026

Efficacy and Safety of Guselkumab Maintenance Therapy in Patients With Moderately to Severely Active Crohn’s Disease: Results Through Week 144 From the Phase 3 GALAXI 2 & 3 Studies

Bruce E. Sands, Walter Reinisch, Geert R. D’Haens, Remo Panaccione, Anita Afzali, David T. Rubin, Jacqueline Yee, Wilbert van Duijnhoven, Christopher Corbett, Rian Van Rampelbergh, Tadakazu Hisamatsu, Silvio Danese


This document will be available on Oct 19th 2026

Efficacy and Safety of the First Co-Antibody Therapy, JNJ-78934804, in Patients With Moderately to Severely Active Crohn’s Disease Refractory to Two or More Systemic Therapy Mechanisms

Vipul Jairath, Geert R. D’Haens, Iris Dotan, Nat A. Terry, Monica Walker, Vanessa Bundy, Hayley Perry, Dylan Richards, Marion L. Vetter, Taku Kobayashi, Stefan Schreiber, Bruce E. Sands


This document will be available on Oct 19th 2026

Efficacy and Safety of the First Co-Antibody Therapy, JNJ-78934804, in Patients With Moderately to Severely Active Ulcerative Colitis Refractory to Two or More Systemic Therapy Mechanisms

Raja Atreya, Bruce E. Sands, Séverine Vermeire, Remo Panaccione, Gregory T. Moore, John Lynch, Melissa G. Marko, Eun Suk Jung, Ruchi Patel, Siyka Alexandrova, Hayley Perry, Marion L. Vetter, Julián Panés, Maria T. Abreu


This document will be available on Oct 20th 2026

Endoscopic Outcomes of Ulcer Size and Ulcerated Surface Over One Year Across Bowel Segments in Participants With Crohn’s Disease Treated With Guselkumab: Pooled GALAXI 2 and GALAXI 3, Phase 3 Trials Analysis

Alessandro Armuzzi, Mathurin Fumery, Bruce E. Sands, Marc Ferrante, Tim Raine, Rian Van Rampelbergh, Maciej Nazar, Victoria McCaffrey, Jacqueline van Denderen, Raja Atreya


This document will be available on Oct 20th 2026

Guselkumab Efficacy in Subgroups of Adults With a History of Inadequate Response or Intolerance to Anti-Tumor Necrosis Factor-Α Therapy and Moderately to Severely Active Crohn’s Disease: Results From the GALAXI 2 & 3 Studies

Walter Reinisch, Remo Panaccione, Geert D, Haens, Tadakazu Hisamatsu, Bruce E Sands, Rian Van Rampelbergh, Wilbert van Duijnhoven, Shashi Adsul, Gustavo Scapini, Silvio Danese, Anita Afzali


This document will be available on Oct 18th 2026

Histologic and Endoscopic Efficacy of Icotrokinra, A First-in-Class Targeted Oral Peptide That Precisely Blocks the IL-23 Receptor, in Ulcerative Colitis: Outcomes From the ANTHEM-UC Study

Britta Siegmund, Jimmy K. Limdi, Edward V. Loftus, Jr., Vipul Jairath, Maria T. Abreu, Minhu Chen, Edouard Louis, Katsuyoshi Matsuoka, Lindsey Surace, Ngozi Erondu, Martha Zeeman, Joyce Zhan, Mary Ellen Frustaci, Grazyna Rydzewska, Karen Chachu


This document will be available on Oct 20th 2026

Imaging Practices and Use of Intestinal Ultrasound For Moderate-to-Severe Inflammatory Bowel Disease: A Multinational Physician Survey in China, Japan, and Germany

Katsuyoshi Matsuoka, Hong Yang, Xiaoxiao Alice Lu, Bo Chen, Ayako Sasaki, Ursula Kleine-Vossbeck, Shashi Adsul, Tiange Liu, Meshal Imran, Yan Wang, Shimin Bi, Han Gao, Rouven Hecht, Lukas Scharfenberger, Keira Herr, Ivana Bravata, Darren Pscitelli, Claudia Ott, Irina Blumenstein


This document will be available on Oct 18th 2026

Pharmacokinetics and Exposure-Response Relationships of Subcutaneous Guselkumab Maintenance in Participants With Moderately to Severely Active Crohn’s Disease

Bruce E. Sands, Geert R. D’Haens, Omoniyi J. Adedokun, Tae Eun Yang, David T. Rubin, Nat A. Terry, Rian Van Rampelbergh, Marion L. Vetter, Tadakazu Hisamatsu, Remo Panaccione, Silvio Danese


This document will be available on Oct 20th 2026

Pharmacokinetics and Exposure-Response Relationships of Subcutaneous Guselkumab Maintenance in Participants With Moderately to Severely Active Ulcerative Colitis

David T. Rubin, Laurent Peyrin-Biroulet, Jie Shao, Yu Kyoung Cho, Jafar Sadik B. Shaik, Millie Long, Silvio Danese, Yelina Alvarez, Marion L. Vetter, Thomas Baker, Jessica R. Allegretti, Tadakazu Hisamatsu


This document will be available on Oct 20th 2026

Physician Opinions on Treatment Preferences and Long-Term Treatment Goals For Moderate-to-Severe Inflammatory Bowel Disease in China, Japan, and Germany

Irina Blumenstein, Hong Yang, Xiaoxiao Alice Lu, Bo Chen, Ayako Sasaki, Ursula Kleine-Vossbeck, Shashi Adsul, Tiange Liu, Meshal Imran, Jia Zhong, Aolin Wang, Han Gao, Rouven Hecht, Lukas Scharfenberger, Keira Herr, Ivana Bravata, Darren Pscitelli, Claudia Ott, Katsuyoshi Matsuoka


This document will be available on Oct 17th 2026

Physician Opinions on Treatment Preferences and Long-Term Treatment Goals in Moderate to Severe Ulcerative Colitis and Crohn’s Disease in Germany

Irina Blumenstein, Xiaoxiao Alice Lu, Ursula Kleine-Vossbeck, Shashi Adsul, Yichen Zhang, Meshal Imran, Jessica Smith, Aolin Wang, Rouven Hecht, Lukas Scharfenberger, Julian Pohlan, Ivana Bravata, Darren Piscitelli, Claudia Ott


This document will be available on Oct 17th 2026

Plasma, Colon Tissue and Fecal Pharmacokinetics of Icotrokinra in ANTHEM-UC: Results Through Week 28 From a Phase 2B Dose-Ranging Study in Ulcerative Colitis Patients

Tristan Baguet, Lindsey Surace, Joyce Zhan, Ngozi Erondu, Mary Ellen Frustaci, Colleen Marano, Vipul Jairath, Maria T. Abreu, Britta Siegmund, An Vermeulen


This document will be available on Oct 17th 2026

Regulation of Fibroblast Biology in Ileum and Rectum By Guselkumab in Crohn’s Disease: Post-Hoc Analysis of GALAXI Ph3 Program

Dylan J. Richards, Patrick Branigan, Hamid Bassiri, Rian Van Rampelbergh, Nat A. Terry, Bradford McRae


This document will be available on Oct 17th 2026

Single-Cell and Spatial Profiling of Cellular Composition and Signaling Changes Following Icotrokinra Treatment in Ulcerative Colitis: Results From ANTHEM-UC

Klebea Sohn, Joshua Rusbuldt, Lynn Tomsho, Daniel Horowitz, Jared Liu, Koichi Hashikawa, Koen Van den Berge, Ewoud De Troyer, Roohid Parast, Martha Zeeman, Lindsey Surace, Ngozi Erondu, Colleen Marano, Dawn Waterworth, Brad McRae, Amy Hart, Arun Kannan, Britta Seigmund, Edouard Louis, Maria T. Abreu


This document will be available on Oct 20th 2026

The Efficacy and Safety of Guselkumab in Patients With Moderate to Severe Ulcerative Colitis Through 2 Years: ASTRO Week 96 Results

Millie Long, Laurent Peyrin-Biroulet, Tadakazu Hisamatsu, Jessica R. Allegretti, Yelina Alvarez, Thomas Baker, Karen Hertzog, Chenglong Han, Hongyan Zhang, Ye Miao, David T. Rubin, Silvio Danese


This document will be available on Oct 18th 2026

Unsupervised Machine Learning to Identify Distinct Patient-Level Response Patterns to Guselkumab in Ulcerative Colitis: Post Hoc Analysis From the ASTRO Trial

Stefan Schreiber, Silvio Danese, Sudheer Rani, Thomas Baker, Yelina Alvarez, Long-Long Gao, Zijiang Yang, Timothy Hoops, Millie Long


This document will be available on Oct 17th 2026

Ustekinumab Exposure During Pregnancy and Risk of Small For Gestational Age in Inflammatory Bowel Disease: Results From the DUMBO Registry of GETECCU

María Chaparro, Ana Garre, Ainhoa Aranguren, Eduardo Leo Carnerero, Cristina Calviño-Suárez, María Dolores Martín Arranz, Marta Calvo, Lucía Zabalba San Martín, Isabel Pérez Martínez, Maite Arroyo, Agnes Fernández-Clotet, Sandra Marín Pedrosa, María Teresa Diz-Lois Palomares, María José Casanova, Vicent Hernández Ramírez, Montserrat Rivero, Alexandra Ruiz Cerulla, Pilar Corsino Roche, José María Huguet, Iván Guerra, Lara Arias, Raquel Camargo Camero, Gemma Valldosera, Ana Bejarano García, Ana Gutiérrez Casbas, Ángeles Masedo, Daniel Hervías, Iago Rodríguez Lago, Miguel Ángel de Jorge, Daniel Ceballos, Luis Bujanda, Pilar López Serrano, Mariam Aguas, Ana Echarri Piudo, Manuel Van Domselaar, Alfredo Lucendo, Carlos Tardillo Marín, Pablo Vega, Marta Maia Boscá Watts, David Busquets Casals, Marta Piqueras Cano, Virginia Robles Alonso, Edisa Mª Armesto González, Beatriz Zuñiga de Mora-Figueroa, Miriam Mañosa, Pau Sendra Rumbeu, Esther Bernardos, Lucía Márquez Mosquera, Patricia Ramírez de La Piscina Urraca, Mari Carmen Rodríguez Grau, Noemí Manceñido, Vanesa Prieto, Laura Ramos, Wendy Xiomara Ladino, Víctor Manuel Navas López, Mª Rocío Plaza Santos, María Curieses, Empar Sainz Arnau, Elena Betoré Glaría, Carlos Castaño Milla, Miguel Sans Cuffi, Antonio García Herola, Gisela Torres Vicente, Sandra Hermida, Nuria Montes, Javier P. Gisbert


This document will be available on Oct 19th 2026

 

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