J&J Medical Connect
TECVAYLI®

(teclistamab-cqyv)

This information is intended for US patients and caregivers to access current scientific information about J&J Innovative Medicine products. It is prepared by Medical Information and is not intended to promote the use of our products, nor to provide medical advice.

What is TECVAYLI?

Last Updated: 04/11/2025

important information about tecvayli  

  • TECVAYLI may cause side effects that are serious, life-threatening or lead to death, including Cytokine Release Syndrome (CRS) and neurologic problems.1
  • Due to the risk of these symptoms, TECVAYLI is only available through the TECVAYLI and TALVEY Risk Evaluation and Mitigation Strategy (REMS).1
    • You will be given a Patient Wallet Card from your healthcare provider that lists signs and symptoms of CRS and neurologic problems. Carry the Patient Wallet Card with you at all times and show it to all of your healthcare providers. You should call your healthcare provider right away if you develop any of the signs or symptoms of CRS and neurologic problems listed below at any time during your treatment:  
      • Cytokine Release Syndrome (CRS): fever (100.4°F or higher), difficulty breathing, chills, dizziness or lightheadedness, fast heartbeat, feeling anxious, confusion or restlessness, headache, increased liver enzymes in your blood
      • Neurologic problems: headache, jerking movements, rigid muscles, feeling restless, numbness and tingling (feeling like “pins and needles”), confusion, trouble speaking, muscle spasms, tremor, double vision, changes in your handwriting, problems walking, muscle weakness in your body or face, hearing loss, burning, throbbing, or stabbing pain

SUMMARY

Here is a passage from the TECVAYLI MEDICATION GUIDE which may be helpful to address your question:

What is TECVAYLI?

  • TECVAYLI is a prescription medicine to treat adults with multiple myeloma who1:
    • have already received at least 4 treatment regimens, including a proteasome inhibitor, an immunomodulatory agent and an anti-CD38 monoclonal antibody to treat their multiple myeloma  
      and
    • their cancer has come back or did not respond to prior treatment
  • It is not known if TECVAYLI is safe and effective in children.1 

ADDITIONAL INFORMATION

This information is provided ONLY in response to your request and is not intended as medical advice, to promote the use of our product, or suggest using it in any manner other than as described in the PRESCRIBING INFORMATION. All decisions regarding your medical treatment should be made with your healthcare professional(s). Please contact your healthcare professional(s) to discuss the information in this response.

Please refer to the attached full PRESCRIBING INFORMATION and the PATIENT MEDICATION GUIDE for TECVAYLI.1

 

References

1 TECVAYLI (teclistamab-cqyv) [Prescribing Information]. Horsham, PA: Janssen Biotech,  Inc.;https://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/TECVAYLI-pi.pdf