SUMMARY

• TECVAYLI is compatible with stainless steel injection needles.¹
• Replace the transfer needle with an appropriately sized needle for injection.¹
• In clinical trials, the following ancillary supplies for preparation and administration were specified²:
  • Preparation: 18-27G needle was required for the preparation of TECVAYLI.²
  • Administration:
    • TECVAYLI step-up doses (10 mg/mL vial) and treatment doses (90 mg/mL vial): 25-31G needle, 8-16 mm in length was required for the administration of TECVAYLI.²
    • TECVAYLI treatment doses (90 mg/mL vial): For administration of TECVAYLI treatment doses, a 25-27G needle, 8-16 mm in length was recommended due to the higher viscosity.²

Literature Search

A literature search of MEDLINE^®, Embase^®, BIOSIS Previews^®, and Derwent Drug File databases (and/or other resources, including internal/external databases) was conducted on 19 February 2025.