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Here is a passage from the LAZCLUZE PATIENT INFORMATION which may be helpful to address your question:

Can LAZCLUZE cause skin problems?

• LAZCLUZE may cause serious side effects, including skin problems.¹
  • LAZCLUZE may cause severe rash including redness, raised acne-like bumps, itching, and dry skin. Tell your healthcare provider right away if you get any skin reactions. Your healthcare provider may start you on an antibiotic for the first 3 months of treatment followed by an antibiotic lotion for your scalp for the next 9 months. During treatment with LAZCLUZE, you should apply a non-comedogenic (does not clog pores) skin moisturizer (ceramidebased or other types of moisturizers that provide longlasting skin hydration and does not include drying ingredients) on your face and whole body (except scalp) and wash your hands and feet every day with 4% chlorhexidine solution. Your healthcare provider may treat you with a medicine(s) or send you to see a skin specialist (dermatologist) if you get skin reactions during treatment with LAZCLUZE.
    • LAZCLUZE can cause skin reactions. You should limit your time in the sun during and for 2 months after your treatment with LAZCLUZE. Wear protective clothing and use broad-spectrum UVA/UVB sunscreen during treatment with LAZCLUZE.

Some of the most common skin side effects of LAZCLUZE when given in combination with amivantamab include rash, infected skin around the nail, and itchy skin.¹ 

Your healthcare provider may temporarily stop, decrease your dose or completely stop your treatment with LAZCLUZE if you have serious side effects.¹

These are not all of the possible side effects of LAZCLUZE.¹

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1800FDA1088.¹

ADDITIONAL INFORMATION

This information is provided ONLY in response to your request and is not intended as medical advice, to promote the use of our product, or suggest using it in any manner other than as described in the PRESCRIBING INFORMATION. All decisions regarding your medical treatment should be made with your healthcare professional(s). Please contact your healthcare professional(s) to discuss the information in this response.

Please refer to the attached full PRESCRIBING INFORMATION and the PATIENT INFORMATION for LAZCLUZE.¹