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icotrokinra

Medical Information

Icotrokinra – Use in Mild Plaque Psoriasis

Last Updated: 03/01/2026

SUMMARY

  • Icotrokinra (JNJ-77242113) is a targeted oral peptide that selectively binds the interleukin-23 (IL-23) receptor and inhibits IL-23 pathway signaling.1 
  • There is no relevant data available regarding the use of icotrokinra in mild plaque psoriasis or in mild psoriasis involving special areas.

Literature Search

A literature search of MEDLINE®, EMBASE®, BIOSIS Previews®, and DERWENT® (and/or other resources, including internal/external databases) was conducted on 09 February 2026.

 

References

1 Bissonnette R, Soung J, Hebert AA, et al. Oral icotrokinra for plaque psoriasis in adults and adolescents. N Engl J Med. 2025;393(18):1784-1795.