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CAPLYTA - Dosing - Maximum Dose

Last Updated: 11/13/2025

SUMMARY  

  • Based on clinical trials, the highest recommended daily dosage of CAPLYTA is 42 mg.1 
  • Johnson and Johnson does not recommend the use of CAPLYTA in a manner that is inconsistent with the prescribing information.

Literature Search

A literature search of MEDLINE®, EMBASE®, BIOSIS Previews®, and DERWENT® (and/or other resources, including internal/external databases) conducted on 13 October 2025 did not identify any relevant citations pertaining to this topic.

 

References

1 CAPLYTA (lumateperone) [Prescribing Information]. Bedminster, NJ: Intra-Cellular Therapies, Inc; https://www.intracellulartherapies.com/docs/caplyta_pi.pdf